In 2011, the United States-based Institute of Medicine (IOM) defined clinical practice guidelines as “statements that include recommendations, intended to optimize patient care, that are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options”.1 In the past two decades, the number of global guidelines, whether in the field of Western medicine, traditional Chinese medicine, or integrated Chinese and Western medicine, has been growing rapidly, and its methodology has become gradually advanced.2, 3, 4, 5 Around the development, implementation, and research of the clinical practice guidelines, professional organizations (such as the Guidelines International Network, GIN6) and working groups (such as the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group,7 Appraisal of Guidelines for Research and Evaluation (AGREE) working group,8 Reporting Items for Practice Guidelines in Healthcare (RIGHT) working group9) have been established. At the same time, the guideline methodologists have naturally become a new profession.10, 11