The causes and degree of research waste occur in four sequential stages. But from our point of view, another very important factor we should consider is the affordability of access to published research articles. How much research is wasted because those who might...The reporting quality of randomised controlled trials is still being perfected. However, reporting guidelines such as CONSORT and PRISMA are not well disseminated and implemented in China.Practice guidelines are an important innovation in patient care. According to the 2011 Institute of Medicine (IOM) definition, practice guidelines are “statements that include recommendations, intended to optimize patient care, that are informed by a systematic review...Yaolong Chen and coworkers analyse the situation and challenges for clinical practice guidelines in China and provide recommendations for their development and implementation.